Philanthropic support has allowed PhD student Amy Holt to explore how aspirin could improve bowel cancer treatments.
I’ve always found cell biology fascinating: the way that cells work, how they build us as human beings and how they can cause disease. It’s what drew me to studying cancer. By learning about what goes wrong in cancer cells, we also learn a lot about normal cells and how they should function.
Bowel cancer has one of the highest mortality rates of any cancer, because it’s often detected at quite a late stage. Researchers have established that taking aspirin for long periods of time decreases your risk of developing bowel cancer. But what we don’t know is exactly why that is. Throughout my PhD, my research group and I have been exploring how aspirin influences cellular functions to make cells less likely to become cancerous and to slow the progression of a cancer. (more…)