As we look back on the maelstrom of 2020 and the continued impact of COVID-19, I hope you will take some solace in the way in which your University has been weathering this storm and continuing to be excellent in all its endeavours.
Researchers, businesses, government and diverse communities must come together to proactively shape our digital future, say Professors Susan Halford and Dimitra Simeonidou, Co-Directors of the University’s Bristol Digital Futures Institute (BDFI).
The BDFI is led by Professor Susan Halford (School of Sociology, Politics and International Studies) and Professor Dimitra Simeonidou (Department of Electrical and Electronic Engineering). For the past decade Professor Halford’s work has focused on the interface between social and computational sciences, while Professor Simeonidou specialises in high-performance networks and future internet research. This complementary expertise feeds into the BDFI, which aims to transform the way we create, utilise and evaluate new digital technologies to benefit our society now and in the future. (more…)
COVID-19: Discovery of a druggable pocket in the SARS-CoV-2 spike protein
When husband-and-wife dynamic duo Professors Imre Berger (Max Planck-Bristol Centre for Minimal Biology) and Christiane Schaffitzel (School of Biochemistry) found themselves in lockdown in March 2020, unable to teach or run their normal workday at the University of Bristol, they did not hang up their lab coats. Instead (while complying with all necessary safety measures) they assembled a cohort of volunteers from their teams and set to work to do what they could to stop COVID-19 in its tracks, as part of the bigger Bristol University COVID-19 Emergency Research Group (UNCOVER). (more…)
COVID-19: Looking at different ways in which aerosol research can support the fight against COVID-19
As Director of the EPSRC Centre for Doctoral Training in Aerosol Science and the Bristol Aerosol Research Centre, Professor Jonathan Reid’s approach to tackling COVID-19 is, naturally, focused on aerosols. ‘Aerosols’ is a term that is used to refer to a collection of particles that are airborne and with sizes typically smaller than the diameter of a human hair. When we speak, breathe, cough or even sing, we generate hundreds of these particles that someone else could breathe in, transmitting the virus responsible for COVID-19.
A key piece of work from Professor Reid has shown that there is significantly less risk of COVID-19 transmission from anaesthesia procedures than was previously thought. This is an important finding at a time when many operations and NHS procedures have been postponed or cancelled, causing problems for patients in the UK.
Since the outset of the COVID-19 pandemic, there has been much debate about the danger to hospital staff from anaesthetic procedures. Concerns include that inserting a tube in the patient’s airway (intubation) before surgery or removing it at the end (extubation) may produce a fine mist of small aerosol particles and spread the COVID-19 virus to nearby staff.
COVID-19: Immune correlates of hyperinflammation and protective immunity in COVID-19
As we grapple with the nightmare scenario of a global pandemic, scientists around the world, including at Bristol, are diving into research around as many aspects of the COVID-19 virus as possible. One of the key findings to date is that in serious cases the body’s immune system goes into ‘overdrive’. Evidence accumulated so far suggests that the life-threatening COVID-19 complications are related to immune dysregulation, arising because of viral infection in the form of a hyperinflammatory syndrome accompanied by increased plasma levels of pro-inflammatory cytokines.(1-2)
Immunologist Dr Laura Rivino is conducting a pilot study that should provide us with a clearer understanding of the immune response underlying both the immunopathology and immune protection in patients with COVID-19. Her team’s hypothesis is that it would be beneficial to use a combination of strategies where the anti-inflammatory response can be blocked while simultaneously boosting the anti-viral immune response, with an expectation of ensuring viral clearance and establishment of immunological memory.
COVID-19: Black lives in lockdown – the pandemic experiences of people with Black, Asian and minority ethnicities living in the South West
For many people, the reports that COVID-19 was disproportionately affecting those in Black, Asian and minority ethnic communities was news to them. For Dr Saffron Karlsen, however, it was not. As Associate Professor in Sociology and a specialist in inequalities in health research, Dr Karlsen has spent over 20 years looking at how structural and societal inequalities hamper health and healthcare for those in ethnic minority groups. (more…)
Rhea Singhal, Founder and CEO of Ecoware – India’s first and largest sustainable food packaging company – tells us about her move from Pharmacology to environmentally friendly tableware, what she learned from her time at Bristol, and how to confidently follow your passion.
I fell in love with Bristol on my open day at the University. The city had such a nice feel to it, not too large but big enough to be interesting. It was easy to navigate as a student and I always felt at home, which was particularly important, as I was an international student. I made a great bunch of friends at Bristol that I’m still in touch with today.
I had wanted to be a medical doctor since I was very little, but when it came to actually attending university I wavered, and I wasn’t so sure. So instead I chose to study Pharmacology. But I found the degree to be very research based and I personally didn’t like that, I wanted more face-to-face interaction. It was very hard, but I also knew that nothing lasts forever. I was also lucky in that the faculty were always super supportive and honestly felt like family. And I loved all of the societies and extracurriculars that I was part of. (more…)
Jonathan graduated from Bristol with a degree in Geology and is now a digital strategy consultant, focusing on communication, collaboration and digital workplace technologies. With 25 years’ blue-chip experience, he is a regular keynote speaker, contributor to the digital community and a recognised global expert. He is also Chair of the Alumni Association Committee at the University of Bristol. (more…)
Since graduating from Bristol in 1989 with a BA in English and Drama, Fiona Clark has had an incredible career. She is a highly experienced strategic leader, successful arts manager, and senior fundraiser whose career spans the arts and voluntary sectors in the UK and internationally. Currently the Festival Director and CEO of the Cork International Film Festival, just some of Fiona’s previous roles have included: Head of Development at the Irish Film Institute, CEO of Get Connected and CEO of Earthrace Ltd.